Search results
-
Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
Hamermesh, Richard G.; Kucherlapati, Raju; Gordon, RachelCase HBS-810066-EEntrepreneurshipIn May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had received approval several years prior. Moreover, Vectibix had also received Food and Drug Administration approval in 2006. During additional trials, Amgen has learned that the Vectibix...Starting at €8.20
-
Radically Simple IT (Spanish version)
Upton, David M.; Staats, Bradley R.Article HBS-R0803JInformation Technologiesthe difficulty and expense of mapping out all requirements before a project starts because people often cannot specify everything that they need beforehand; the other unanticipated needs that almost always arise once a system is in operation; and the tricky task of persuading people to use and "own" it. Japan's Shinsei Bank emerged during the authors' research as a standout among the companies applying the path-based method. The firm designed, b...Starting at €8.20
-
The Indego Africa Project (Spanish Version)
McGinn, Kathleen L.; Gordon, RachelCase HBS-914S10Dos abogados jóvenes que se encuentran y comienzan a construir el Proyecto África Indego, una asociación de ONG con cooperativas de mujeres en Ruanda. Indego conecta las cooperativas en el mercado minorista internacional de productos artesanales hechos a mano, ayuda a las cooperativas construyen su capacidad de negocio, y desarrolla y ofrece formación en el aula en la vida y habilidades de negocio para los miembros de la cooperativa. En el moment...Starting at €8.20
-
Storming into the U.S. Market (Spanish version)
Bartlett, Christopher A.; Gordon, Rachel; Lafkas, JohnCase HBS-918S10StrategyThe RoboTech case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative product (a specialized surgical robot) in an unfamiliar market segment (spinal surgery) and decides to enter the unfamiliar, distant U.S. healthcare market, which is characteri...Starting at €8.20
-
Intrapreneurship within FLG, Inc. (Spanish version)
Garvin, David A.; Gordon, RachelCase HBS-918S11EntrepreneurshipThis case follows Jenica Fletcher as she rebuilds her company's guitar strings division from the ground up. Convinced that she could turn the division around if given complete independence from corporate headquarters, Fletcher relocated the group, rebranded it as Malenti Strings, repositioned the guitar strings as high-performance products, and transformed Malenti into a fast-growing, profitable business. The case traces Fletcher's key steps in...Starting at €8.20
-
Differences at Work: Alex (A) (Spanish version)
Sucher, Sandra J.; Gordon, RachelCase HBS-408S50Leadership and People ManagementIn Differences at Work: Alex (A), HBS Case No. 9-408-011 Alex has been asked an inappropriate question by the interviewer at an interview for his dream job. How will Alex handle the situation? Should he accept the position is offered?Starting at €8.20
-
Lean Knowledge Work
Staats, Bradley R.; Upton, David M.Article HBS-R1110G-EService and Operations ManagementMany manufacturing companies and some service firms have reaped considerable benefits by applying variations of the Toyota Production System, a method for making operations "lean" through relentless efforts to increase quality and efficiency and eliminate waste. But conventional wisdom holds that lean principles don't lend themselves to knowledge work, which involves judgment and expertise, not the sorts of repetitive, easily specified tasks foun...Starting at €8.20
-
Adnexus Therapeutics, Inc.: Considering the Exit
Sato, Vicki L.; Gordon, RachelCase HBS-609015-EService and Operations ManagementDr. John Mendlein, CEO of Adnexus Therapeutics Inc., (Adnexus), a private biotechnology company, must decide whether to pursue acquisition talks with Bristol-Myers Squibb (BMS) after a successful six month collaboration or continue with Adnexus' planned IPO.Starting at €8.20
-
Dartmouth-Hitchcock Medical Center: Spine Care
Huckman, Robert S.; Porter, Michael E.; Gordon, Rachel; Kindred, NatalieCase HBS-609016-EStrategyDescribes the Spine Center at Dartmouth-Hitchcock Medical Center, a multidisciplinary unit that offers patients suffering from spinal problems "one-stop" access to a range of providers including orthopedic surgeons, neurosurgeons, neurologists, medical specialists in physical medicine and pain management, mental health providers, and occupational and physical therapists. The Center was created to address what its founder, James Weinstein, M.D., s...Starting at €8.20
-
Daewoo Shipbuilding and Marine Engineering
Upton, David M.; Kim, BowonCase HBS-609018-EService and Operations ManagementExplores the journey of aggressive learning and capability building in the operations of a major Korean Shipbuilder. While DSHM had once used its superior learning capability to topple its Japanese competition, it now faced the potential for a similar attack from new Chinese competitors. Without outsourcing some of its work to China, DSHM would become uncompetitive. However, in outsourcing the work, some skills would necessarily have to be transf...Starting at €8.20