HBSP (USA)
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Adaptive Platform Trials: The Clinical Trial of the Future
Stern, Ariel D.; Mehta, SarahCase HBS-618025-EService and Operations ManagementIn July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial-an adaptive platform trial-to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer. Alexander believed that the standard way in which new cancer drugs were tested-the traditional randomized controlled trial (RCT)-was limited in many ways. While statistically rigorous and s...Starting at €8.20
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Maven Clinic: Women's Health in the Digital Age
Stern, Ariel D.; Mehta, SarahCase HBS-620035-EStrategyIn late 2017, Kate Ryder, the founder and CEO of digital women's health telemedicine company Maven Clinic, faced an important decision. Maven offered both a direct to consumer (D2C) product that anyone could use to book virtual appointments with health practitioners across a range of services and specialties for a fee, and an enterprise product-the Maven Family Benefits platform-which it sold to large employers as an employee benefit. Since found...Starting at €8.20
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Twine Health
Huckman, Robert S.; Stern, Ariel D.; Preble, MatthewCase HBS-615068-EService and Operations ManagementIn late 2014, Dr. John Moore (CEO), Frank Moss (chairman), and Scott Gilroy (CTO) of Twine Health (Twine) had to resolve several challenges that threatened to restrict the widespread dissemination of its sole product, Twine. Twine was a cloud-based platform that enabled patients to create and manage chronic disease treatment plans in conjunction with their primary care providers and specialized coaches. Twine had already enjoyed impressive succes...Starting at €8.20
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Adaptive Platform Trials: The Clinical Trial of the Future (B)
Stern, Ariel D.; Mehta, SarahCase HBS-620001-EEntrepreneurshipThis case provides an update to the (A) case, which introduces students to adaptive platform trials, an ambitious, more efficient type of clinical trial that increases access to therapies. The A case centers on Dr. Brian Alexander's efforts to launch an adaptive platform trial for studying potential therapies for glioblastoma (GBM), an aggressive form of brain cancer. The (B) case provides an update and explores the strategies that Alexander is c...Starting at €5.74