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Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
Hamermesh, Richard G.; Kucherlapati, Raju; Gordon, RachelCase HBS-810066-EEntrepreneurshipIn May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had received approval several years prior. Moreover, Vectibix had also received Food and Drug Administration approval in 2006. During additional trials, Amgen has learned that the Vectibix...Starting at €8.20
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Technology and Human Vulnerability (Spanish version)
Turkle, Sherry; Coutu, Diane L.Article HBS-R0309BService and Operations ManagementFor most of the last 50 years, technology knew its place. It's very different today. Technology is not only ubiquitous but has become highly intrusive as well. On the Internet, people invent imaginary identities in virtual chat rooms. Children are growing up with interactive toy animals. If we want to be sure we'll like who we've become in 50 years, we need to take a closer look at the psychological effects of current and future technologies. The...Starting at €8.20
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Escoger ganadores: una conversación con el director de MacArthur Fellows Program, Daniel J. Scolow
Socolow, Daniel J.; Coutu, Diane L.Article HBS-R0705HLeadership and People ManagementEn el mundo de los negocios, "creatividad" se ha convertido en la última moda. ¿Cómo atraer, nutrir y dirigir al pueblo de extraordinario talento que se van a plantear con el siguiente Lipitor, Sony Walkman, o iPod es un tema duradera entre los empresarios. A medida que el director del Programa de Becarios MacArthur, Daniel J. Socolow tiene una experiencia considerable con el proceso de erradicar a la creatividad. En esta conversación con el edit...Starting at €8.20
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The Indego Africa Project (Spanish Version)
McGinn, Kathleen L.; Gordon, RachelCase HBS-914S10Dos abogados jóvenes que se encuentran y comienzan a construir el Proyecto África Indego, una asociación de ONG con cooperativas de mujeres en Ruanda. Indego conecta las cooperativas en el mercado minorista internacional de productos artesanales hechos a mano, ayuda a las cooperativas construyen su capacidad de negocio, y desarrolla y ofrece formación en el aula en la vida y habilidades de negocio para los miembros de la cooperativa. En el moment...Starting at €8.20
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Storming into the U.S. Market (Spanish version)
Bartlett, Christopher A.; Gordon, Rachel; Lafkas, JohnCase HBS-918S10StrategyThe RoboTech case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative product (a specialized surgical robot) in an unfamiliar market segment (spinal surgery) and decides to enter the unfamiliar, distant U.S. healthcare market, which is characteri...Starting at €8.20
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Intrapreneurship within FLG, Inc. (Spanish version)
Garvin, David A.; Gordon, RachelCase HBS-918S11EntrepreneurshipThis case follows Jenica Fletcher as she rebuilds her company's guitar strings division from the ground up. Convinced that she could turn the division around if given complete independence from corporate headquarters, Fletcher relocated the group, rebranded it as Malenti Strings, repositioned the guitar strings as high-performance products, and transformed Malenti into a fast-growing, profitable business. The case traces Fletcher's key steps in...Starting at €8.20
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Differences at Work: Alex (A) (Spanish version)
Sucher, Sandra J.; Gordon, RachelCase HBS-408S50Leadership and People ManagementIn Differences at Work: Alex (A), HBS Case No. 9-408-011 Alex has been asked an inappropriate question by the interviewer at an interview for his dream job. How will Alex handle the situation? Should he accept the position is offered?Starting at €8.20
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Spotting Patterns on the Fly: A Conversation with Birders David Sibley and Julia Yoshida (Spanish version)
Sibley, David; Yoshida, Julia; Coutu, Diane L.Article HBS-R0211BStrategyRecognizing and anticipating change in industry patterns is a core competence for companies today, allowing managers to capitalize on opportunities before they are apparent to others. Yet, companies are far from mastering how to recognize such patterns, especially at the strategic level, where information is usually less profuse and much less precise. Pattern recognition is not a new skill, though, at least not to people outside the business worl...Starting at €8.20
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Adnexus Therapeutics, Inc.: Considering the Exit
Sato, Vicki L.; Gordon, RachelCase HBS-609015-EService and Operations ManagementDr. John Mendlein, CEO of Adnexus Therapeutics Inc., (Adnexus), a private biotechnology company, must decide whether to pursue acquisition talks with Bristol-Myers Squibb (BMS) after a successful six month collaboration or continue with Adnexus' planned IPO.Starting at €8.20
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Dartmouth-Hitchcock Medical Center: Spine Care
Huckman, Robert S.; Porter, Michael E.; Gordon, Rachel; Kindred, NatalieCase HBS-609016-EStrategyDescribes the Spine Center at Dartmouth-Hitchcock Medical Center, a multidisciplinary unit that offers patients suffering from spinal problems "one-stop" access to a range of providers including orthopedic surgeons, neurosurgeons, neurologists, medical specialists in physical medicine and pain management, mental health providers, and occupational and physical therapists. The Center was created to address what its founder, James Weinstein, M.D., s...Starting at €8.20