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Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
Hamermesh, Richard G.; Kucherlapati, Raju; Gordon, RachelCase HBS-810066-EEntrepreneurshipIn May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had received approval several years prior. Moreover, Vectibix had also received Food and Drug Administration approval in 2006. During additional trials, Amgen has learned that the Vectibix...Starting at €8.20
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Digital Equipment Corp.: The Endpoint Model (A) (Spanish Version)
Garvin, David A.; Simpson, JanetCase HBS-605S11Service and Operations ManagementDescribe una estrategia de fabricación integral diseñado para reducir sustancialmente el tiempo de ciclo de órdenes (es decir, el tiempo entre la colocación de un pedido por un cliente y su entrega al cliente). Para poner en marcha la estrategia digital ha adoptado la fabricación de planificación de recursos (MRP II). El caso permite a los estudiantes para evaluar los pros y los contras de la estrategia que requiere una rápida información fluye y...Starting at €8.20
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Change Through Persuasion (Spanish version)
Garvin, David A.; Roberto, Michael A.Article HBS-R0502FLeadership and People ManagementThis article includes a one-page preview that quickly summarizes the key ideas and provides an overview of how the concepts work in practice along with suggestions for further reading. Faced with the need for a massive change, most managers respond predictably. They revamp the organization's strategy, shift around staff, and root out inefficiencies. They then wait patiently for performance to improve--only to be bitterly disappointed because they...Starting at €8.20
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From Concept to Production (A) (Spanish version)
Garvin, David A.; Field, Lee C.; Simpson, JanetCase HBS-606S20Service and Operations ManagementDescribes the evolution of the Boeing 767 from the conception of the project to the start of manufacturing. Shows how the company manages an enormously complex and risky project and introduces students to a variety of estimating and management tools. The decision issue involves the shift from three-person to two-person cockpits and whether rework should be done in-line (without removing planes from the flow of production) or off-line (after initi...Starting at €8.20
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General Electric--Thermocouple Manufacturing (A) (Spanish Version)
Garvin, David A.; Detreville, SuzanneCase HBS-607S08Service and Operations ManagementGE está considerando la introducción de un sistema de producción "just-in-time" para reducir el inventario en su área de fabricación termopar. Los estudiantes de casos se presenta con una descripción del actual sistema de gestión de inventario, el proceso de producción, y las perspectivas de diferentes personas en la planta. La cuestión es cómo GE debe proceder con la introducción de este sistema.Starting at €8.20
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PPG: Developing a Self-Directed Work Force (A) (Spanish Version)
Garvin, David A.; Klein, NormanCase HBS-609S15Service and Operations ManagementPPG ha construido una planta de vidrio del estado de la técnica en Berea, Kentucky. La planta está persiguiendo el objetivo de una "fuerza de trabajo autodirigido." El caso describe el progreso hasta la fecha y los problemas no resueltos de gestión. Estos incluyen preguntas sobre rotación de turnos, las oportunidades de promoción, evaluación y supervisión de los empleados, el papel de los empleados en el establecimiento de la política, y si es o ...Starting at €8.20
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Developing Software through Crowdsourcing (Spanish version)
Lakhani, Karim R.; Garvin, David A.; Lonstein, EricCase HBS-610S21StrategyTopCoder's crowdsourcing-based business model, in which software is developed through online tournaments, is presented. The case highlights how TopCoder has created a unique two-sided innovation platform consisting of a global community of over 225,000 developers who compete to write software modules for its over 40 clients. Provides details of a unique innovation platform where complex software is developed through ongoing online competitions. B...Starting at €8.20
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Transition at DataCo (Spanish Version)
Cespedes, Frank V.; Knoop, Carin-IsabelCase HBS-818S06EntrepreneurshipEl fundador de una compañía de análisis de datos, Stefan Brecht, tiene varios problemas con su desarrollador de negocios clave y el jefe de marketing y ventas, Tamara Smithson. Smithson, un alquiler principios que habían sido fundamentales en la construcción de la empresa funciona como un miembro, no se atreve a delegar tareas y clientes, y, como Brecht lo ve "a menudo pone los asuntos del cliente por delante de las necesidades y procedimientos d...Starting at €8.20
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The Indego Africa Project (Spanish Version)
McGinn, Kathleen L.; Gordon, RachelCase HBS-914S10Dos abogados jóvenes que se encuentran y comienzan a construir el Proyecto África Indego, una asociación de ONG con cooperativas de mujeres en Ruanda. Indego conecta las cooperativas en el mercado minorista internacional de productos artesanales hechos a mano, ayuda a las cooperativas construyen su capacidad de negocio, y desarrolla y ofrece formación en el aula en la vida y habilidades de negocio para los miembros de la cooperativa. En el moment...Starting at €8.20
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Maximizing Revenues in the Minor Leagues (Spanish version)
Cespedes, Frank V.; Winig, Laura; Lovelock, Christopher H.Case HBS-209S22MarketingWhen students have the English-language PDF of this Brief Case in a coursepack, they will also have the option to purchase an audio version. The marketing director of a new minor-league baseball team must design, conduct, and then interpret survey research to determine optimal ticket pricing that will yield large attendance figures and contribute to the owner's goal of breaking even in the first year of play. The pricing assignment becomes more c...Starting at €8.20